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Moderate to Severe Pain
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Suritram Tablet is a prescription medicine that is used for the short-term management of moderate to severe pain. This medicine works by blocking the reuptake of natural chemicals (norepinephrine and serotonin) which produce pain in the body.
Dosage & Administration
An initial dose of two tablets of Tramadol hydrochloride/Paracetamol is recommended. Additional doses can be taken as needed, not exceeding 8 tablets (equivalent to 300 mg tramadol hydrochloride and 2600 mg paracetamol) per day.
A dose adjustment is not usually necessary in patients up to 75 years without clinically manifest hepatic or renal insufficiency. In elderly patients over 75 years elimination may be prolonged. Therefore, if necessary the dosage interval is to be extended according to the patient's requirements.
Because of the presence of tramadol, the use of Tramadol hydrochloride/Paracetamol is not recommended in patients with severe renal insufficiency (creatinine clearance < 10 ml/min). In cases of moderate renal insufficiency (creatinine clearance between 10 and 30 ml/min), the dosing should be increased to 12-hourly intervals. As tramadol is removed only very slowly by haemodialysis or by haemofiltration, post dialysis administration to maintain analgesia is not usually required.
- Better safety profile vs.Diclofenac and COX-2 inhibitors
- Long term safety, less GI irritations
- Lower treatment costs (vs. COX-2 inhibitors)
- Approved indication for moderate & severe pain.